Seed train optimization for suspension cell culture
نویسندگان
چکیده
منابع مشابه
Seed train optimization for suspension cell culture
Introduction The purpose of a seed train is the generation of an adequate number of cells for the inoculation of a production bioreactor. This is timeand cost-intensive: From volumes used for cell thawing or cell line maintenance the cell number has to be increased. The cells are usually run through many cultivation systems which become larger with each passage (e.g. T-flasks, roller bottles or...
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Cell culture seed trains-the generation of a sufficient viable cell number for the inoculation of the production scale bioreactor, starting from incubator scale-are time- and cost-intensive. Accordingly, a seed train offers potential for optimization regarding its layout and the corresponding proceedings. A tool has been developed to determine the optimal points in time for cell passaging from ...
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ژورنال
عنوان ژورنال: BMC Proceedings
سال: 2013
ISSN: 1753-6561
DOI: 10.1186/1753-6561-7-s6-p9